Evidential Analysis of Genetic Association Data.
The evidential approach employs the Law of Likelihood, and uses the LR (likelihood ratio)
rather than p-values to plan/design, analyze, interpret and replicate genetic association studies.
Here is a R package that implements the evidential approach to analyze genetic association SNP data.
Strug, L.J et al. A pure likelihood approach to the analysis of genetic association data: an alternative to Bayesian and frequentist analysis.
EJHG. Epub Apr 28, 2010. PMID: 20424645
- version 1.0.0 (Mar 19, 2010): evian_1.0.tar.gz.
version 1.0.1 (Apr 13, 2010): evian_1.0.1.tar.gz. (w/robust, mle inversion fix, 2df plot title fix)
version 1.0.2 (Apr 15, 2010): evian_1.0.2.tar.gz. (robust example in vignette/demo, listterms length fix, as.vector() for char covariates fix)
version 1.1.0 (May 6, 2010): evian_1.1.0.tar.gz. (NEW w/ Linear regression functions)
version 1.1.0 (May 17, 2010): evian_1.1.0.zip. (For windows)
- Current documentation: online or PDF.
- Evian vignette.
Included in the package is a sample dataset and a demo. After installing and loading
package, run R commands:
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