Evidential Analysis of Genetic Association Data.

The evidential approach employs the Law of Likelihood, and uses the LR (likelihood ratio)
rather than p-values to plan/design, analyze, interpret and replicate genetic association studies.
Here is a R package that implements the evidential approach to analyze genetic association SNP data.

Strug, L.J et al. A pure likelihood approach to the analysis of genetic association data: an alternative to Bayesian and frequentist analysis.
EJHG. Epub Apr 28, 2010. PMID: 20424645

R package

  1. version 1.0.0 (Mar 19, 2010): evian_1.0.tar.gz.
    version 1.0.1 (Apr 13, 2010): evian_1.0.1.tar.gz. (w/robust, mle inversion fix, 2df plot title fix)
    version 1.0.2 (Apr 15, 2010): evian_1.0.2.tar.gz. (robust example in vignette/demo, listterms length fix, as.vector() for char covariates fix)
    version 1.1.0 (May 6, 2010): evian_1.1.0.tar.gz. (NEW w/ Linear regression functions)
    version 1.1.0 (May 17, 2010): evian_1.1.0.zip. (For windows)

  2. Current documentation: online or PDF.

  3. Evian vignette.

    Included in the package is a sample dataset and a demo. After installing and loading package, run R commands:

    R> library(evian)
    R> demo(evian)

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